ExiTron nano 12000

CT angiography agent

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ExiTron nano 12000 CT contrast agent (1 x 5 injections): 130 - 095 - 698
ExiTron nano 12000 CT contrast agent (5 x 5 injections): 130 - 095 - 700

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ExiTron nano 12000 is an innovative nanoparticulate agent optimized for high-resolution CT angiography. Its remarkably high contrast and long blood half-life enable clear visualization of fine vascular structures including microvessels.

Profit from the unique nanoparticulate agent for high-resolution CT angiography:

  • Highlight vascular structures and regions of increased vascular permeability
  • Benefit from the strong and long-lasting blood vessel contrast allowing high-resolution CT studies including functional cardiac imaging
  • The low injection volume and high biological tolerability allows studies even in weak animals
  • ExiTron nano 12000 is Viscover's leading agent for high-resolution CT angiography

Apply ExiTron nano 12000 to:

  • Effectively visualize vascular structures down to the microvessel level
  • Detect areas of increased vascular permeability, e.g. certain types of tumors
  • Investigate functional cardiac parameters
  • Benefit from the liver imaging capability analogous to ExiTron nano 6000
Physico-chemical properties and structure
Mean hydrodynamic diameter:

~110 nm

Hounsfield units (undiluted agent):

~12000 HU

Schematic diagram of an ExiTron nano 12000 nanoparticle

ExiTron nano 12000 CT angiography
Volume-rendered CT angiography of the mouse thorax with visualization of the beating heart, thoracic bones and major blood vessels of the heart.
Selected references
  1. Boll, H. et al. (2011) Micro-CT based experimental liver imaging using a nanoparticulate contrast agent longitudinal study in mice. PLoS ONE 6: e25692.
  2. Lalwani, K. et al. (2013) Contrast Agents for Quantitative MicroCT of Lung Tumors in Mice.
    Comp Med. 63(6): 482-90.
  3. Flechsig, P. et al. (2015) A Comparison of microCT and microPET for Evaluating Lymph Node Metastasis in a Rat Model. Mol Imaging Biol. 18(2): 243-248.
  4. Das, N.M. et al. (2016) In Vivo Quantitative Microcomputed Tomographic Analysis of Vasculature and Organs in a Normal and Diseased Mouse Model. PLoS One 11(2): e0150085.