ExiTron nano 12000

CT angiography agent

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ExiTron nano 12000 CT contrast agent (1 x 5 injections): 130 - 095 - 698
ExiTron nano 12000 CT contrast agent (5 x 5 injections): 130 - 095 - 700

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ExiTron nano 12000 is an innovative nanoparticle agent for CT angiography, liver imaging, and the detection of liver tumors and metastases. As the concentrated counterpart to ExiTron nano 6000, ExiTron nano 12000 has been optimized for high-resolution CT angiography.

Profit from the unique nanoparticulate agent for CT angiography:

  • Optimally visualize vasculature by a concentrated formulation of ExiTron nano 6000
  • Benefit from typical injection volume of only 100 µL in mice, which greatly enhances cardiovascular tolerability compared to conventional agents
  • ExiTron nano 12000 is Viscover's leading agent for CT angiography and visualization of fine structures

Utilize the clear advantage of ExiTron nano 12000 over existing agents to:

  • Study vascular structures down to the microvessel level
  • Gain from the liver imaging capability analogous to ExiTron nano 6000
Physico-chemical properties and structure
Mean hydrodynamic diameter:

~110 nm

Hounsfield units (undiluted agent):

~12000 HU

Schematic diagram of an ExiTron nano 12000 nanoparticle

ExiTron nano 12000 CT angiography
Volume-rendered CT angiography in mouse using ExiTron nano 12000. The inferior vena cava and the renal vascular tree are clearly visible.
Selected references
  1. Boll, H. et al. (2011) Micro-CT based experimental liver imaging using a nanoparticulate contrast agent longitudinal study in mice. PLoS ONE 6: e25692.
  2. Lalwani, K. et al. (2013) Contrast Agents for Quantitative MicroCT of Lung Tumors in Mice.
    Comp Med. 63(6): 482-90.
  3. Flechsig, P. et al. (2015) A Comparison of microCT and microPET for Evaluating Lymph Node Metastasis in a Rat Model. Mol Imaging Biol. 18(2): 243-248.
  4. Das, N.M. et al. (2016) In Vivo Quantitative Microcomputed Tomographic Analysis of Vasculature and Organs in a Normal and Diseased Mouse Model. PLoS One 11(2): e0150085.