NiraWave Rocker

Optical agent for imaging of tumors

Order no:

NiraWave Rocker optical imaging agent (1 x 5 injections): 130 - 095 - 158
NiraWave Rocker optical imaging agent (5 x 5 injections): 130 - 095 - 159

price per item:
€495.00
Excluding VAT and shipping costs

NiraWave Rocker is a nanoparticulate near-infrared (NIR) fluorescence imaging agent optimized for visualization of primary tumors and metastases. Its accumulation in tumor cells via the rocker-switch mechanism as well as its strong fluorescence and high stability enable visualization of tumors in animal cancer models.

NiraWave Rocker, the unique optical imaging agent:

  • Is based on a nanoparticle with a high intrinsic fluorescene intensity
  • Highlights primary and metastatic tumors
  • Exhibits stable fluorescence enabling longtime visualization of tumors
  • NiraWave Rocker is Viscover's leading optical imaging agent for visualization of tumors

Apply NiraWave Rocker to:

  • Detect primary tumors and metastases based on its selective enrichment
  • Study tumor progression in tumor-bearing mouse models
  • Monitor therapeutic response
Physico-chemical properties and structure
Emission wavelength:

830 nm

Excitation wavelength:

660 - 790 nm

Schematic diagram of a NiraWave Rocker nanoparticle

Normalized absorption and emission spectra of NiraWave Rocker in plasma

NiraWave Rocker optical imaging of mouse tumors
Accumulation of NiraWave Rocker in tumors of a mouse model of human A549 lung adenocarcinoma...

Top: Accumulation of NiraWave Rocker in tumors of a mouse model of human A549 lung adenocarcinoma (left) and murine T1 mammary carcinoma (right).

Bottom: Optical image of a mouse mopdel of human prostate cancer (PC-3) showing accumulation od NiraWave Rocker in primary tumor as well as in metastasized sciatic lymph nodes

and murine T1 mammary carcinoma.
Optical image of a mouse mopdel of human prostate cancer (PC-3) showing accumulation od NiraWave Rocker in primary tumor as well as in metastasized sciatic lymph nodes.
Selected references
  1. Hess, M et al. (2016) Long-term tumor visualization by NiraWave Rocker.
Further information
window.addEventListener("load", (event) => { setTimeout(function () { $( 'footer .head' ).on( 'click', function ( event ) { $( this ).parent().find( '.widget' ).slideToggle( 400 ); $( this ).toggleClass( 'active' ); } ); }, 1000); var footer = document.querySelector('footer'); footer.innerHTML = footer.innerHTML.replaceAll('(tm)', ''); });