GadoSpin M

Proven extracellular MRI agent

Order no:

GadoSpin M MRI contrast agent (1 x 5 injections): 130 - 095 - 134
GadoSpin M MRI contrast agent (5 x 5 injections): 130 - 095 - 135

price per item:
€260.00
Excluding VAT and shipping costs

GadoSpin M is our all-purpose extracellular gadolinium chelate agent for classical contrast-enhanced MRI and for studying CNS diseases. The trusted standard from human clinical MRI has been formulated for small animal imaging.

The trusted all-purpose MRI agent from clinical practice:

  • Is rapidly distributed in vascular and interstitial space
  • Does not permeate membranes or the intact blood-brain barrier
  • GadoSpin M is Viscover's tried and tested extracellular MRI agent

Rely on a substance that is well-proven in clinical practice for the:

  • Investigation of blood-brain barrier abnormalities in brain tumors and neuroinflammation
  • Delineation of tissues based on its differential distribution
Physico-chemical properties and structure

Relaxivity (37 °C, 1.5T)

In plasma:

r1 = 4 L mmol-1 s-1
r2 = 5 L mmol-1 s-1

In water:

r1 = 3 L mmol-1 s-1
r2 = 4 L mmol-1 s-1

Molecular weight:

938 g mol-1

Structural formula of Gd-DTPA:

GadoSpin M brain tumor and whole body MRI
Intracranial tumor in mouse exhibits contrast enhancement after GadoSpin M has passed the compromised blood-brain barrier. The image series shows tumor progression.
Mouse whole body images offer enhanced soft-tissue contrast by using GadoSpin M. Three slices of the dataset are shown.
Top Series:
Intracranial tumor in mouse exhibits contrast enhancement after GadoSpin M has passed the compromised blood-brain barrier. The image series shows tumor progression.
Bottom Series:
Mouse whole body images offer enhanced soft-tissue contrast by using GadoSpin M. Three slices of the dataset are shown.
Selected references
  1. Kiessling, F. et al. (2003) Dynamic T1-weighted monitoring of vascularization in human carcinoma heterotransplants by magnetic resonance imaging. Int. J. Cancer 104: 113-120.
  2. Li, P. et al. (2016) Use of micro-positron emission tomography with 18F-fallypride to measure the levels of dopamine receptor-D2 and 18F-FDG as molecular imaging tracer in the pituitary glands and prolactinomas of Fischer-344 rats. Onco Targets Ther. 9: 2057-68.
  3. Furman-Haran, E. et al. (1996) Angiogenic response of MCF7 human breast cancer to hormonal treatment: assessment by dynamic GdDTPA-enhanced MRI at spatial resolution. J. Magn. Reson. Imaging 6: 195-202.
  4. Bjørnaes, I. et al. (2000) Measurement of the extracellular volume of human melanoma xenografts by contrast enhanced magnetic resonance imaging. Magn. Reson. Imaging 18: 41-48.
Further information