NiraWave nano 780

Optical angiography agent

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NiraWave nano 780 optical imaging agent (1 x 5 injections): 130 - 095 - 695
NiraWave nano 780 optical imaging agent (5 x 5 injections): 130 - 095 - 693

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420.00
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NiraWave nano 780 is a nanoparticulate optical imaging agent for the visualization of vascular fine structure as well as angiogenic processes in tumors and inflammation. It provides a broad excitation range, a high quantum yield and best possible tissue penetration due to fluorescence in the near-infrared range.

NiraWave nano 780, the nanoparticle optical imaging agent:

  • Exhibits a high Stokes-shift and high resistance towards bleaching
  • Is optimized for an extended circulation time
  • Enables a wide imaging time window
  • Viscover's leading agent for optical angiography
  • Visualize the vascular fine structure
  • Study angiogenesis in tumors and inflammation
Physico-chemical properties and structure
Emission wavelength:

780 nm

Excitation wavelength:

below 740 nm

Schematic diagram of a NiraWave nano 780 nanoparticle



Absorption and emission spectra of
NiraWave nano 780

NiraWave nano 780 nanoparticle optical angiography
Optical angiography in mouse injected with NiraWave nano 780. The fine structure of blood vessels is clearly visible, for example, in the hind limbs.
Color-coded image of the same animal showing a vascularized tumor in the hind limb.

Left:Top: Optical angiography in mouse injected with NiraWave nano 780. The fine structure of blood vessels is clearly visible, for example, in the hind limbs.

Right:Bottom: Color-coded image of the same animal showing a vascularized tumor in the hind limb.

Selected references
  1. Ballou, B. et al. (2004) Noninvasive imaging of quantum dots in mice. Bioconjugate Chem. 15:79-86.
  2. Gao, X. et al. (2004) In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotechnol.
    22(8): 969-976.
  3. So, M.K. et al. (2006) Self-illuminating quantum dot conjugates for in vivo imaging. Nat. Biotechnol. 24(3): 339-343.
  4. Kuka, J. et al. (2015) Dual Modality Fluorescence and Computed Tomography System for Small Animal In Vivo Imaging. ICNP, Riga, Latvia, p31.

 
Further information