NiraWave™ nano 780
Optical angiography agent
NiraWave™ nano 780 optical imaging agent (1 x 5 injections): 130 - 095 - 695
NiraWave™ nano 780 optical imaging agent (5 x 5 injections): 130 - 095 - 693
NiraWave nano 780 is a nanoparticulate optical imaging agent for the visualization of vascular fine structure as well as angiogenic processes in tumors and inflammation. It provides a broad excitation range, a high quantum yield and best possible tissue penetration due to fluorescence in the near-infrared range.
NiraWave nano 780, the nanoparticle optical imaging agent:
- Exhibits a high Stokes-shift and high resistance towards bleaching
- Is optimized for an extended circulation time
- Enables a wide imaging time window
- Viscover's leading agent for optical angiography
Apply NiraWave nano 780 to:
- Visualize the vascular fine structure
- Study angiogenesis in tumors and inflammation
below 740 nm
Schematic diagram of a NiraWave nano 780 nanoparticle
Absorption and emission spectra of
NiraWave nano 780
Left:Top: Optical angiography in mouse injected with NiraWave nano 780. The fine structure of blood vessels is clearly visible, for example, in the hind limbs.
Right:Bottom: Color-coded image of the same animal showing a vascularized tumor in the hind limb.
- Ballou, B. et al. (2004) Noninvasive imaging of quantum dots in mice. Bioconjugate Chem. 15:79-86.
- Gao, X. et al. (2004) In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotechnol.
- So, M.K. et al. (2006) Self-illuminating quantum dot conjugates for in vivo imaging. Nat. Biotechnol. 24(3): 339-343.
- Kuka, J. et al. (2015) Dual Modality Fluorescence and Computed Tomography System for Small Animal In Vivo Imaging. ICNP, Riga, Latvia, p31.