MRI of atherosclerotic plaque
In vivo longitudinal monitoring of plaque progression by GadoSpinTM F
In this study we developed an MRI method using the innovative MRI agent GadoSpin F to monitor plaque progression in ApoE-/- mice. Through measurements of the plaque size and contrast-to-noise ratio (CNR) at various disease stages, we demonstrated that MRI monitoring of plaque burden within the same animal is feasible even at short time intervals of 5 weeks.
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